ABOUT US
Our family started The Perricelli Hope Foundation in 2016 after our daughter, Julia’s, successful outcome battling a brain tumor in 2015. We have learned an enormous amount about pediatric brain tumors and their treatment over the past couple of years. What has really stuck with us is the fact that there is a lack of funding for pediatric cancers and that brain tumors are being treated with toxic chemotherapy medications that were developed in the 1950’s. The prognosis for the majority of children diagnosed with brain tumors is very grave and over 30% of children diagnosed with a brain tumor will die.
Once we were through the initial shock and crisis of a brain tumor diagnosis for one of our children, our thoughts turned to how fortunate we are given Julia’s positive outcome and long-term prognosis. We now feel a strong desire to help others who are not as lucky as Julia. By asking our physicians where we can get involved, we learned about the Children’s Brain Tumor Consortium (CBTTC). The CBTTC is composed of fifteen of the world’s leading children’s hospitals working collaboratively to find better, more effective and less toxic treatments for brain tumors. The CBTTC has collected more than 13,000 samples from close to 2,000 patient subjects, making the CBTTC the largest open-access pediatric brain tumor biorepository in the world. The CBTTC also collects associated clinical data to facilitate the genomic analysis of bio specimens. Cell lines are developed and transplantable tumor models are then created from biopsy specimens. These models allow researchers to share their findings with other CBTTC member institutions and with the world-wide scientific community.
Through this collaborative effort the CBTTC has provided specimens and their underlying clinical and genomic data free of charge to numerous research projects on the condition that the study results are released to advance medical research. Although pediatric brain tumors fall into the category of “rare disease, “ far too many children are dying from brain tumors or living with the debilitating side effects from the tumors or the treatments. It is our hope that through the ground breaking research that is supported by the CBTTC we will find a cure for all pediatric brain tumors. Learn more about the CBTTC
Once we were through the initial shock and crisis of a brain tumor diagnosis for one of our children, our thoughts turned to how fortunate we are given Julia’s positive outcome and long-term prognosis. We now feel a strong desire to help others who are not as lucky as Julia. By asking our physicians where we can get involved, we learned about the Children’s Brain Tumor Consortium (CBTTC). The CBTTC is composed of fifteen of the world’s leading children’s hospitals working collaboratively to find better, more effective and less toxic treatments for brain tumors. The CBTTC has collected more than 13,000 samples from close to 2,000 patient subjects, making the CBTTC the largest open-access pediatric brain tumor biorepository in the world. The CBTTC also collects associated clinical data to facilitate the genomic analysis of bio specimens. Cell lines are developed and transplantable tumor models are then created from biopsy specimens. These models allow researchers to share their findings with other CBTTC member institutions and with the world-wide scientific community.
Through this collaborative effort the CBTTC has provided specimens and their underlying clinical and genomic data free of charge to numerous research projects on the condition that the study results are released to advance medical research. Although pediatric brain tumors fall into the category of “rare disease, “ far too many children are dying from brain tumors or living with the debilitating side effects from the tumors or the treatments. It is our hope that through the ground breaking research that is supported by the CBTTC we will find a cure for all pediatric brain tumors. Learn more about the CBTTC
